Objective To investigate the infection status and epidemic characteristics of Severe fever with thrombocytopenia syndrome (SFTS) virus (SFTSV) in different domestic animals in Tiantai County, Zhejiang Province, China, so as to provide basis for SFTS prevention and control. Methods Serum samples were collected from pigs, cattle, sheep, chickens, ducks, and geese for double-antigen sandwich enzyme-linked immunosorbent assay of total SFTSV antibody. Multivariable logistic regression model was used to analyze the associations of SFTSV infection with the factors. Results In 2023, a total of 2 439 serum samples were collected from the six animal species, and the total positive rate was 17.51% (427/2 439). The infection rates of SFTSV in cattle, pigs, sheep, ducks, geese, and chickens were 35.05% (190/542), 25.34% (74/292), 16.80% (145/863), 4.17% (2/48), 3.33% (1/30), and 2.26% (15/664), respectively. Multivariable analysis showed that the positive rate of total SFTSV antibody in domestic animals in areas with more than 10 cases (37.26%) was higher than those in areas with 1-10 cases (13.29%) and 0 cases (9.56%), the positive rate of SFTSV antibody in mountain area (30.57%) was higher than those in towns (14.33%) and subdistricts (10.70%), and the positive rate of SFTSV antibody was higher in cattle (35.05%) than in sheep (16.80%) and in chickens (2.26%)(all P<0.05). Conclusions SFTSV infection was detected in different domestic animals and townships of Tiantai County in Zhejiang Province, but with various positive rates, suggesting that comprehensive measures such as animal management, tick control, and personal protection publicity can be implemented before peak season of SFTS in key areas in Tiantai County to effectively reduce the incidence of the disease.
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