Epidemiological characteristics of scrub typhus in Qingdao, Shandong Province, China, 2006-2022

PAN Bei, DONG Li-yan, HAN Ya-lin, HU Xiao-wen, JIA Jing, LYU Kun-zheng

doi:10.11853/j.issn.1003.8280.2024.06.009

Chinese Journal of Vector Biology and Control >

2024 , Vol. 35 >Issue 6: 676 - 680

DOI: https://doi.org/10.11853/j.issn.1003.8280.2024.06.009

Vector-borne Disease

Epidemiological characteristics of scrub typhus in Qingdao, Shandong Province, China, 2006-2022

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Department of Infectious Disease Control and Prevention, Qingdao Municipal Center for Disease Control and Prevention, Qingdao Institute of Prevention Medicine, Qingdao, Shandong 266000, China

Received date: 2024-06-04

Online published: 2024-12-20

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Abstract

Objective To analyze the time, regional, and population distribution of scrub typhus cases reported in Qingdao, Shandong Province, China, so as to provide a scientific basis for the prevention and control of scrub typhus in the future. Methods The information on scrub typhus cases in Qingdao from 2006 to 2022 was collected and statistically analyzed by Excel 2010 and SPSS 22.0 softwares. The incidence rate as well as characteristics and variation trends of time, regional, and population distribution of scrub typhus were analyzed by the joinpoint regression and Chi-square test. Results From 2006 to 2022, 1 112 cases of scrub typhus were reported in Qingdao, with an average annual incidence of 0.74/100 000, and no death cases were reported. Scrub typhus cases were reported from March to December, of which October and November were the peak months of reported incidence, with cases accounting for 96.13% of the total cases. Scrub typhus cases were reported in all age groups, with a significant difference in the incidence rate (χ²=1 266.119, P<0.001). Males in the 60-<65 years old group (93 cases) and females in the 55-<60 years old group (106 cases) had the highest cases reported. The top five cities (districts) in average annual incidence were Laixi City (2.42/100 000), Jimo District (1.49/100 000), Huangdao District (1.11/100 000), Jiaozhou City (0.58/100 000), and Pingdu City (0.40/100 000), with a significant difference in the reported incidence (χ²=1 050.577, P<0.001). Farmer (85.16%) was ranked the first in occupation for scrub typhus infection. Conclusions The incidence of scrub typhus in Qingdao from 2006 to 2022 presents significant regional and seasonal variations. Farmers are at high risk of scrub typhus. It is suggested that extensive health education about scrub typhus prevention and control should be carried out for key populations in key areas, and multiple effective measures should be taken to strengthen the surveillance of vectors and host animals and control the infection level of scrub typhus.

Key words： Scrub typhus; Epidemiological characteristic; Surveillance; Influencing factor

Cite this article

PAN Bei, DONG Li-yan, HAN Ya-lin, HU Xiao-wen, JIA Jing, LYU Kun-zheng . Epidemiological characteristics of scrub typhus in Qingdao, Shandong Province, China, 2006-2022[J]. Chinese Journal of Vector Biology and Control, 2024 , 35(6) : 676 -680 . DOI: 10.11853/j.issn.1003.8280.2024.06.009

References

[1] Chen QQ, Zhang YG, Liu YM, et al. Serological diagnosis of tsutsugamushi disease and gene sequence analysis of Orientia tsutsugamushi in northern area of Anhui[J]. Dis Surveill, 2022, 37（3）:377-380. DOI:10.3784/jbjc.202105100257.（in Chinese）陈晴晴, 张永根, 刘一梅, 等. 安徽省北方地区恙虫病血清学诊断和病原体基因序列分析[J]. 疾病监测, 2022, 37（3）:377-380. DOI:10.3784/jbjc.202105100257.
[2] Ye MZ, Zhang NW. Analysis on the epidemiological and clinical characteristics of scrub typhus in Sanming City from 2015 to 2021[J]. Appl Prev Med, 2022, 28（5）:438-441, 445. DOI:10.3969/j.issn.1673-758X.2022.05.006.（in Chinese）叶敏贞, 张南文. 2015－2021年三明市恙虫病流行病学和临床特征分析[J]. 应用预防医学, 2022, 28（5）:438-441, 445. DOI:10.3969/j.issn.1673-758X.2022.05.006.
[3] Li GC, Liu QY. Epidemic trend of scrub typhus in the world[J]. Dis Surveill, 2018, 33（2）:129-138. DOI:10.3784/j.issn.1003-9961.2018.02.006.（in Chinese）李贵昌, 刘起勇. 恙虫病的流行现状[J]. 疾病监测, 2018, 33（2）:129-138. DOI:10.3784/j.issn.1003-9961.2018.02.006.
[4] Li W, Li GC, Liu XB, et al. Research progress in epidemiological characteristics and influencing factors of scrub typhus[J]. Chin J Vector Biol Control, 2020, 31（6）:738-743. DOI:10.11853/j.issn.1003.8280.2020.06.025.（in Chinese）李文, 李贵昌, 刘小波, 等. 恙虫病流行特征及影响因素研究进展[J]. 中国媒介生物学及控制杂志, 2020, 31（6）:738-743. DOI:10.11853/j.issn.1003.8280.2020.06.025.
[5] Xin HL, Fu P, Sun JL, et al. Risk mapping of scrub typhus infections in Qingdao City, China[J]. PLoS Negl Trop Dis, 2020, 14（12）:e0008757. DOI:10.1371/journal.pntd.0008757.
[6] Liu QY, Liu XB, Chang N, et al. Advances and achievements in the surveillance and control of vectors and vector-borne diseases in China, 2012-2021[J]. Chin J Vector Biol Control, 2022, 33（5）:613-621, 654. DOI:10.11853/j.issn.1003.8280.2022.05.001.（in Chinese）刘起勇, 刘小波, 常楠, 等. 2012－2021年我国媒介生物及相关传染病监测控制进展及成效[J]. 中国媒介生物学及控制杂志, 2022, 33（5）:613-621, 654. DOI:10.11853/j.issn.1003.8280.2022.05.001.
[7] Yang YF, Wang JL, Yao YC, et al. Investigation of the first scrub typhus epidemic in Shandong Province[J]. Chin J Epidemiol, 1987, 8（5）:280. DOI:10.3760/cma.j.issn.0254-6450.1987.05.109.（in Chinese）杨玉富, 王均利, 姚允超, 等. 山东省首次发现恙虫病流行的调查[J]. 中华流行病学杂志, 1987, 8（5）:280. DOI:10.3760/cma.j.issn.0254-6450.1987.05.109.
[8] Liu FD, Wang ZL, Liu DY, et al. Winter scrub typhus was first reported in Wulian County, Shandong Province[J]. Chin J Zoonoses, 1987, 3（5）:40-41. （in Chinese）刘丰东, 王足亮, 刘冬莹, 等. 山东五莲县首次发现冬季恙虫病[J]. 中国人兽共患病杂志, 1987, 3（5）:40-41.
[9] Liu DB, Xu XH, Mao YP, et al. Investigation report of the first scrub typhus outbreak in Laizhou City[J]. Dis Surveill, 1998, 13（12）:470-471. DOI:10.3784/j.issn.1003-9961.1998.12.470.（in Chinese）刘东波, 徐雪华, 毛云鹏, 等. 莱州市首次恙虫病暴发流行的调查报告[J]. 疾病监测, 1998, 13（12）:470-471. DOI:10.3784/j.issn.1003-9961.1998.12.470.
[10] Qin KG, Yang SL, Zhang LY, et al. Clinical analysis of the first epidemic of scrub typhus in Qingzhou City, Shandong Province[J]. Chin J Parasit Dis, 2002, 15（5）:insert 12. DOI:10.3969/j.issn.1673-5234.2002.05.043.（in Chinese）秦开贵, 杨淑玲, 张兰英, 等. 山东省青州市恙虫病首次流行的临床分析[J]. 中国寄生虫病防治杂志, 2002, 15（5）:插页12. DOI:10.3969/j.issn.1673-5234.2002.05.043.
[11] Zhang JY, Feng KJ, Kou ZQ, et al. Epidemiological characteristics and spatial aggregation of scrub typhus in Shandong Province, 2012-2020[J]. Chin J Zoonoses, 2023, 39（9）:865-871, 878. DOI:10.3969/j.issn.1002-2694.2023.00.100.（in Chinese）. 张金艳, 冯开军, 寇增强, 等. 2012－2020年山东省恙虫病流行特征及空间聚集性分析[J]. 中国人兽共患病学报, 2023, 39（9）:865-871, 878. DOI:10.3969/j.issn.1002-2694.2023.00.100.
[12] Zhang M, Wang XJ, Zhao ZT. Current epidemic status and issues on prevention and control of scrub typhus[J]. Chin J Epidemiol, 2011, 32（4）:419-423. DOI:10.3760/cma.j.issn.0254-6450.2011.04.021.（in Chinese）张萌, 王显军, 赵仲堂. 中国恙虫病流行态势及预防控制[J]. 中华流行病学杂志, 2011, 32（4）:419-423. DOI:10.3760/cma.j.issn.0254-6450.2011.04.021.
[13] Liu YX, Zhao ZT, Yang ZQ, et al. Epidemiological investigation of host animals of autumn and winter type scrub typhus in Shandong region[J]. Chin J Epidemiol, 2004, 25（2）:183. DOI:10.3760/j.issn:0254-6450.2004.02.034.（in Chinese）刘运喜, 赵仲堂, 杨占清, 等. 山东地区秋冬型恙虫病宿主动物流行病学调查[J]. 中华流行病学杂志, 2004, 25（2）:183. DOI:10.3760/j.issn:0254-6450.2004.02.034.
[14] Liu YX, Zhao ZT, Wu QY, et al. Investigation on the vectors of scrub typhus in the foci of Shandong Province[J]. Mod Prev Med, 2004, 31（5）:676-678, 684. DOI:10.3969/j.issn.1003-8507.2004.05.012.（in Chinese）刘运喜, 赵仲堂, 吴钦永, 等. 山东地区秋冬型恙虫病传播媒介的调查研究[J]. 现代预防医学, 2004, 31（5）:676-678, 684. DOI:10.3969/j.issn.1003-8507.2004.05.012.
[15] Tan XH, Peng ZQ, Lin WQ, et al. Epidemiological characteristics trends and death related influencing factors of scrub typhus, Guangdong[J]. Mod Prev Med, 2022, 49（23）:4259-4266, 4293. DOI:10.20043/j.cnki.MPM.202204552.（in Chinese）谭小华, 彭志强, 林文青, 等. 广东省恙虫病流行特征时空变化趋势及死亡影响因素分析[J]. 现代预防医学, 2022, 49（23）:4259-4266, 4293. DOI:10.20043/j.cnki.MPM.202204552.
[16] Wu YC, Li QH, Zhang WY, et al. Research progress on epidemic characteristics and risk factors of scrub typhus[J]. J Public Health Prev Med, 2015, 26（2）:70-74. DOI:CNKI:SUN:FBYF.0.2015-02-021.（in Chinese）吴义城, 李青华, 张文义, 等. 恙虫病流行特征及危险因素研究进展[J]. 公共卫生与预防医学, 2015, 26（2）:70-74. DOI:CNKI: SUN: FBYF.0.2015-02-021.
[17] Qiu B, Zhang MG, Yu SD, et al. Analysis of epidemiological trends of hemorrhagic fever with renal syndrome in its present surveillance sites in Qingdao[J]. Chin J Vector Biol Control, 2012, 23（5）:464-466. （in Chinese）邱波, 张名广, 于式德, 等. 青岛市肾综合征出血热监测点疫情流行趋势分析[J]. 中国媒介生物学及控制杂志, 2012, 23（5）:464-466.
[18] Li GC, Wang YJ, Mu QZ, et al. An investigation of the hosts, vectors, and pathogens of scrub typhus in Pinggu natural focus of Beijing, China[J]. Chin J Vector Biol Control, 2021, 32（3）:291-297. DOI:10.11853/j.issn.1003.8280.2021.03.007.（in Chinese）李贵昌, 王玉姣, 母群征, 等. 北京市平谷区恙虫病自然疫源地宿主、媒介和病原体调查[J]. 中国媒介生物学及控制杂志, 2021, 32（3）:291-297. DOI:10.11853/j.issn.1003.8280.2021.03.007.
[19] Chen AX, Tian C, Yang X, et al. Research progress on the distribution of scrub typhus vector chigger mites in China[J]. Chin J Hyg Insect Equip, 2022, 28（6）:556-561. DOI:10.19821/j.1671-2781.2022.06.021.（in Chinese）陈安喜, 田诚, 杨晓, 等. 我国恙虫病媒介恙螨分布的研究进展[J]. 中华卫生杀虫药械, 2022, 28（6）:556-561. DOI:10.19821/j.1671-2781.2022.06.021.
[20] Chen AX, Kong WR, Tian Y, et al. Epidemiological characteristics of scrub typhus in Changzhou, Jiangsu Province, China, 2012-2021[J]. Chin J Vector Biol Control, 2023, 34（3）:372-377. DOI:10.11853/j.issn.1003.8280.2023.03.015.（in Chinese）陈安喜, 孔卫荣, 田野, 等. 江苏省常州市2012－2021年恙虫病流行特征分析[J]. 中国媒介生物学及控制杂志, 2023, 34（3）:372-377. DOI:10.11853/j.issn.1003.8280.2023.03.015.

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