Epidemiological characteristics of re-emergence of human canine-type zoonotic visceral leishmaniasis in Jingxing County, Hebei Province, China

NIU Xiao-wei, ZHAO Xin-yu, ZHOU Ji-kun

doi:10.11853/j.issn.1003.8280.2024.02.013

Chinese Journal of Vector Biology and Control >

2024 , Vol. 35 >Issue 2: 200 - 204

DOI: https://doi.org/10.11853/j.issn.1003.8280.2024.02.013

Vector-borne Disease

Epidemiological characteristics of re-emergence of human canine-type zoonotic visceral leishmaniasis in Jingxing County, Hebei Province, China

Expand

1. School of Public Health of Hebei Medical University, Shijiazhuang, Hebei 050017, China;
2. Center for Disease Control and Prevention of Jingxing, Shijiazhuang, Hebei 050399, China;
3. Medical Research Institute of Shijiazhuang Fifth Hospital, Shijiazhuang, Hebei 050024, China

Received date: 2023-11-13

Online published: 2024-05-09

Fold

Abstract

Objective To investigate the disease distribution characteristics and Leishmania infection status of its hosts and vectors of canine-type zoonotic visceral leishmaniasis in Jingxing County, Hebei Province, China, and to propose targeted control measures to effectively eliminate the epidemic.Methods The data of human kala-azar cases reported in Hebei Province during 2019 to 2023 were collected from the Infectious Disease Reporting Information Management System of China Information System for Disease Control and Prevention. Descriptive epidemiological methods were used to retrospectively analyze the temporal, spatial, and population distributions of human kala-azar with Excel 2017. From February to September 2022, blood samples of all dogs in townships where kala-azar cases were reported were collected, and serum antibodies to Leishmania were examined using rk39 immunochromatographic strips; the antibody-positive rate was calculated and compared between different townships using the Chi-square test with the use of SPSS 25 software. From May to September 2022, sandflies were monitored using the lamp trap method in the poultry sheds or livestock farms of the reported patients, and pathogen classification and identification were performed.Results A total of 32 confirmed cases of kala-azar were reported in Jingxing County, including 23 males and 8 females (sex ratio:2.9:1). All the cases lived in rural areas, 84.38 % of them were farmers, and 81.25 % of them were middle-aged and elderly people over 40 years old. A total of 683 canine blood samples were collected from six townships of Jingxing County, 219 of which were positive for anti-Leishmania antibodies, with a positive rate of 32.01 %. The positive rate of anti-Leishmania antibodies in dogs was significantly different in different townships (χ²=15.609, P=0.008). A total of 852 Phlebotomus chinensis sandflies were captured in Jingxing County, including 665 females and 187 males, with a mean density of 15.07 individuals/lamp·night.Conclusions The epidemic situation of kala-azar in Jingxing county is in the early stage of development. According to the epidemic factors of kala-azar in this area, comprehensive control measures such as personal protection, vector control and pest host control should be taken.

Key words： Kala-azar; Canine-type zoonotic; Epidemiological characteristic; Vector sandfly; Control measure

Cite this article

NIU Xiao-wei, ZHAO Xin-yu, ZHOU Ji-kun . Epidemiological characteristics of re-emergence of human canine-type zoonotic visceral leishmaniasis in Jingxing County, Hebei Province, China[J]. Chinese Journal of Vector Biology and Control, 2024 , 35(2) : 200 -204 . DOI: 10.11853/j.issn.1003.8280.2024.02.013

References

[1] Wu XB,Liu K,Shao ZJ.Epidemic status and control measures of visceral leishmaniasis worldwide[J].Chin J Hyg Insect Equip,2023,29(3):271-276.DOI:10.19821/j.1671-2781.2023.03.021.(in Chinese) 吴旭斌,刘昆,邵中军.全球内脏利什曼病流行现状与防控进展[J].中华卫生杀虫药械,2023,29(3):271-276.DOI:10.19821/j.1671-2781.2023.03.021.
[2] Yang HJ,Sun JL,Zheng CJ,et al.Epidemiological characteristics of visceral leishmaniasis in China,2017-2021[J].Dis Surveill,2023,38(6):676-681.DOI:10.3784/jbjc.202303020076.(in Chinese) 杨慧军,孙军玲,郑灿军,等.2017-2021年全国内脏利什曼病流行特征分析[J].疾病监测,2023,38(6):676-681.DOI:10.3784/jbjc.202303020076.
[3] Zhou ZB,Pan GQ,Li YY,et al.Prevalence of visceral leishmaniasis in China in 2021[J].Chin J Parasitol Parasit Dis,2023,41(2):149-155.DOI:10.12140/j.issn.1000-7423.2023.02.004.(in Chinese) 周正斌,潘改芹,李元元,等.2021年我国内脏利什曼病疫情分析[J].中国寄生虫学与寄生虫病杂志,2023,41(2):149-155.DOI:10.12140/j.issn.1000-7423.2023.02.004.
[4] Zhang PJ,Zhou ZB,Li YY,et al.Prevalence of mountain-zoonotic type visceral leishmaniasis in Yangquan City of Shanxi Province from 2015 to 2020[J].Chin J Schisto Control,2022,34(5):493-499.DOI:10.16250/j.32.1374.2022135.(in Chinese) 张佩君,周正斌,李元元,等.2015-2020年山西省阳泉市犬源型内脏利什曼病疫情调查[J].中国血吸虫病防治杂志,2022,34(5):493-499.DOI:10.16250/j.32.1374.2022135.
[5] Yang CY,He ZQ,Lu DL,et al.Epidemiological investigation on cases of visceral leishmaniasis in Henan Province in 2020[J].Chin J Parasitol Parasit Dis,2022,40(4):481-486.DOI:10.12140/j.issn.1000-7423.2022.04.010.(in Chinese) 杨成运,贺志权,鲁德领,等.2020年河南省内脏利什曼病病例的流行病学调查[J].中国寄生虫学与寄生虫病杂志,2022,40(4):481-486.DOI:10.12140/j.issn.1000-7423.2022.04.010.
[6] Zheng YH,Bai YF,Tie P,et al.Epidemiological characteristics of visceral leishmaniasis in Shanxi Province,2010-2019[J].Chin J Parasitol Parasit Dis,2021,39(3):352-358.DOI:10.12140/j.issn.1000-7423.2021.03.009.(in Chinese) 郑玉华,白永飞,帖萍,等.2010-2019年山西省人群内脏利什曼病流行特征分析[J].中国寄生虫学与寄生虫病杂志,2021,39(3):352-358.DOI:10.12140/j.issn.1000-7423.2021.03.009.
[7] Health Commission of Hebei Province.Summary of prevention and control of parasitic diseases in Hebei Province[J].Chin J Parasitol Parasit Dis,1995,13Suppl 1:S86-88.(in Chinese) 河北省卫生厅.河北省寄生虫病防治工作总结[J].中国寄生虫学与寄生虫病杂志,1995,13增刊1:86-88.
[8] Duan XH.Retrospective investigation and analysis of 82 cases of leishmaniasis in Yangquan City,Shanxi Province[J].Med J Shanxi,2021,50(13):2019-2020.DOI:10.3969/j.issn.0253-9926.2021.13.001.(in Chinese) 段秀红.山西省阳泉市82例黑热病病例回顾性调查分析[J].山西医药杂志,2021,50(13):2019-2020.DOI:10.3969/j.issn.0253-9926.2021.13.001
[9] Li F,Yang JK,Yang CM,et al.Awareness survey of knowledge about prevention and treatment on kala-azar in medical staff from epidemic areas[J].Bull Dis Control Prev,2021,36(5):31-33.DOI:10.13215/j.cnki.jbyfkztb.2106009.(in Chinese) 李凡,杨俊克,杨成明,等.黑热病流行区疾控与医疗机构人员防治知识知晓调查[J].疾病预防控制通报,2021,36(5):31-33.DOI:10.13215/j.cnki.jbyfkztb.2106009.
[10] Ling P,Wang XF,Zhao Y,et al.Analysis of epidemic characteristics of leishmaniasis from Sichuan Center for Disease Control and Prevention,2015 to 2019[J].J Prev Med Chin PLA,2020,38(4):63-65.DOI:10.13704/j.cnki.jyyx.2020.04.019.(in Chinese) 凌攀,王晓凤,赵仪,等.2015-2019年四川省疾控黑热病病例流行特征分析[J].解放军预防医学杂志,2020,38(4):63-65.DOI:10.13704/j.cnki.jyyx.2020.04.019.
[11] Zhang P,Shen ZY,Zhang YP,et al.Research progress of clinical epidemiology,prevention and treatment on visceral leishmaniasis[J].Med J Natl Defend Forces Northwest China,2019,40(11):703-708.DOI:10.16021/j.cnki.1007-8622.2019.11.010.(in Chinese) 张鹏,沈兆媛,张亚萍,等.我国内脏利什曼病临床流行病学特征与防治研究现状[J].西北国防医学杂志,2019,40(11):703-708.DOI:10.16021/j.cnki.1007-8622.2019.11.010.
[12] Zheng YH,Tie P,Bai YF,et al.Investigation on visceral leishmaniasis in domestic dogs and sandfly density in epidemic area in Shanxi Province from 2021 to 2022[J].Chin J Parasitol Parasit Dis,2023,41(4):470-475.DOI:10.12140/j.issn.1000-7423.2023.04.012.(in Chinese) 郑玉华,帖萍,白永飞,等.2021-2022年山西省内脏利什曼病流行区家犬感染情况及白蛉密度调查[J].中国寄生虫学与寄生虫病杂志,2023,41(4):470-475.DOI:10.12140/j.issn.1000-7423.2023.04.012.
[13] Wu Y,Tian XJ,Qi ZQ,et al.Epidemiological and clinical characteristics of 39 cases of visceral leishmaniasis in China[J].J Pathogen Biol,2021,16(3):324-327,331.DOI:10.13350/j.cjpb.210317.(in Chinese) 吴云,田小军,齐志群,等.39例内脏利什曼病的流行病学和临床特征分析[J].中国病原生物学杂志,2021,16(3):324-327,331.DOI:10.13350/j.cjpb.210317.
[14] Wang FF,Zhang PJ,Ren MZ,et al.Epidemiological characteristics of visceral leishmaniasis in Yangquan City,Shanxi Province from 2006 to 2021[J].Chin J Parasitol Parasit Dis,2023,41(2):228-232.DOI:10.12140/j.issn.1000-7423.2023.02.017.(in Chinese) 王芬芬,张佩君,任梦枝,等.2006-2021年山西省阳泉市内脏利什曼病流行特征分析[J].中国寄生虫学与寄生虫病杂志,2023,41(2):228-232.DOI:10.12140/j.issn.1000-7423.2023.02.017.
[15] Han S,Wu WP,Xue CZ,et al.Endemic status of visceral leishmaniasis in China from 2004 to 2016[J].Chin J Parasitol Parasit Dis,2019,37(2):189-195.DOI:10.12140/j.issn.1000-7423.2019.02.013.(in Chinese) 韩帅,伍卫平,薛垂召,等.2004-2016年中国内脏利什曼病疫情分析[J].中国寄生虫学与寄生虫病杂志,2019,37(2):189-195.DOI:10.12140/j.issn.1000-7423.2019.02.013.
[16] Zhang HW,Liu Y,Yang CY,et al.Promoting visceral leishmaniasis from control to elimination in China based on One Health approach[J].J Trop Dis Parasitol,2022,20(4):181-184.DOI:10.3969/j.issn.1672-2302.2022.04.001.(in Chinese) 张红卫,刘颖,杨成运,等.以全健康理念推进我国内脏利什曼病从控制走向消除[J].热带病与寄生虫学,2022,20(4):181-184.DOI:10.3969/j.issn.1672-2302.2022.04.001.
[17] Luo ZW,Zhou ZB,Gong YF,et al.Current status and challenges of visceral leishmaniasis in China[J].Chin J Parasitol Parasit Dis,2022,40(2):146-152.DOI:10.12140/j.issn.1000-7423.2022.02.003.(in Chinese) 罗卓韦,周正斌,公衍峰,等.我国内脏利什曼病的流行现状和防控挑战[J].中国寄生虫学与寄生虫病杂志,2022,40(2):146-152.DOI:10.12140/j.issn.1000-7423.2022.02.003.
[18] Gu ZQ,Wu SX,Cui FZ,et al.A bionomic investigation and analysis of sandflies,the vectors of kala-azar,in Sanmenxia,Henan Province,China[J].Chin J Vector Biol Control,2021,32(5):590-593.DOI:10.11853/j.issn.1003.8280.2021.05.016.(in Chinese) 谷增齐,武恕星,崔法曾,等.河南省三门峡市黑热病媒介白蛉生态调查分析[J].中国媒介生物学及控制杂志,2021,32(5):590-593.DOI:10.11853/j.issn.1003.8280.2021.05.016.
[19] Carvalho AG,Luz JGG,Rodrigues LD,et al.Factors associated with Leishmania spp.infection in domestic dogs from an emerging area of high endemicity for visceral leishmaniasis in Central-Western Brazil[J].Res Vet Sci,2019,125:205-211.DOI:10.1016/j.rvsc.2019.06.013.
[20] Alves GB,de Oliveira TCB,Rodas LC,et al.Efficacy of imidacloprid/flumethrin collar in preventing canine leishmaniosis in Brazil[J].Transbound Emerg Dis,2022,69(5):e2302-e2311.DOI:10.1111/TBED.14571.

Options

Outlines

模态框（Modal）标题

Abstract

Cite this article

References