Special Topics|Tick

Analysis of action pathway of anti-tick subunit vaccine

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  • College of Life Sciences, Hebei Normal University, Shijiazhuang, Hebei 050024, China

Received date: 2022-06-08

  Online published: 2022-10-14

Supported by

Natural Science Foundation of Hebei Province of China (No.C2021205010);Foundation of Hebei Normal University (No.L2020Z06).

Abstract

Ticks are obligate,hematophagous ectoparasites that transmit a variety of pathogens.Although tick control is principally dependent on the application of chemical acaricides at present,long-term application can lead to resistance to acaricides in ticks and cause environmental contamination.Anti-tick subunit vaccine is one of the effective tick control strategies,but its mechanism of action is still unclear.This paper focuses on the host immune responses induced by the anti-tick subunit vaccine,including humoral immunity,cellular immunity,and complement system,as well as the action pathways of antibodies,immune cells,and complement from the host immunized on ticks,in order to lay the foundation for revealing the immune mechanism of anti-tick vaccine and provide a scientific basis for screening for a new anti-tick vaccine.

Cite this article

DONG Hong-meng, WU Ya-xue, HU Yong-hong . Analysis of action pathway of anti-tick subunit vaccine[J]. Chinese Journal of Vector Biology and Control, 2022 , 33(5) : 655 -660 . DOI: 10.11853/j.issn.1003.8280.2022.05.008

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