Objective To study the epidemic features of chikungunya fever outbreak in Quzhou and to explore the effective prevention and control strategies for this disease in the future. Methods All probable cases were chosen by epidemiological individual survey. Dengue and chikungunya virus nucleic acid testing were conducted by real-time quantitative reverse transcription polymerase chain reaction in individual survey. Results Among all samples tested 4 cases were positive for Chikungunya virus. One of the detected cases had a history of travel to Bangladesh. The remaining 3 local cases lived with the first confirmed case in the save village and had no travel record. The epidemic was efficiently controlled by case finding, mosquito eradication and ecological improvement, etc. Conclusion These are the first autochthonous cases reported that was caused by imported chikungunya fever in Zhejiang province. Enhanced entry-exit quarantine, case follow-up in clinical facilities, and vector surveillance are crucial for preventing epidemic of chikungunya.
ZHAO Rui-fang, YU Xin, ZHENG Kai-zeng
. Epidemiological investigation on chikungunya fever outbreak in Quzhou, Zhejiang province, China[J]. Chinese Journal of Vector Biology and Control, 2018
, 29(5)
: 505
-507
.
DOI: 10.11853/j.issn.1003.8280.2018.05.022
[1] Powers AM,Logue CH. Changing patterns of Chikungunya virus:re-emergence of a zoonotic arbovirus[J]. J Gen Virol,2007,88(9):2363-2377. DOI:10.1099/vir.0.82858-0.
[2] Simon F,Savini H,Parola P. Chikungunya:a paradigm of emergence and globalization of vector-borne diseases[J]. Med Clin North Am,2008,92(6):1323-1343. DOI:10.1016/j.mcna. 2008.07.008.
[3] Powers AM,Brault AC,Tesh RB,et al. Re-emergence of chikungunya and o'nyong-nyong viruses:evidence for distinct geographical lineages and distant evolutionary relationships[J]. J Gen Virol,2000,81(2):471-479. DOI:10.1099/0022-1317-81-2-471.
[4] 余樟有,王小林,胡晓龙. 衢州市蚊蝇密度监测及防治效果分析[J]. 中国媒介生物学及控制杂志,2011,22(4):380-382.
[5] 黄鹂,张显光,张文,等. 广东出入境检验检疫局口岸输入性基孔肯雅热监测分析[J]. 中国媒介生物学及控制杂志,2013,24(4):357-360. DOI:10.11853/j.issn.1003.4692.2013.04.025.
[6] 张蓓,沈立松. 实时荧光定量PCR的研究进展及其应用[J]. 国外医学临床生物化学与检验学分册,2003,24(6):327-329. DOI:10.3969/j.issn.1673-4130.2003.06.009.
[7] 袁军,张海林. 全球基孔肯雅热流行现状及分子流行病学研究进展[J]. 中国媒介生物学及控制杂志,2009,20(5):490-493.
[8] Kumar NP,Joseph R,Kamaraj T,et al. A226V mutation in virus during the 2007 chikungunya outbreak in Kerala,India[J]. J Gen Virol,2008,89(Pt 8):1945-1948. DOI:10.1099/vir.0. 83628-0.
[9] 熊劲光,黄振宇,陈平华,等. 一起登革热和一起基孔肯雅热暴发疫情的对比分析[J]. 中华疾病控制杂志,2012,16(4):328-331.
[10] Zhang QL,He JF,De W,et al. Maiden outbreak of chikungunya in Dongguan city,Guangdong province,China:epidemiological characteristics[J]. PLoS One,2012,7(8):e42830. DOI:10.1371/journal.pone.0042830.