Objective We studied the DFR (different region)-type data of Yersinia pestis in Xinlong county and provided a scientific basis for prevention and treatment of plague. Methods One strain of Y. pestis isolated from plague foci in Xinlong county compared with 16 strains of Y. pestis isolated from other plague foci in Ganzi Tibeian Autonomous Prefecture, and genotyped by primers of 23 DFRs and PMT1. To confirm the genotype of strains from Xinlong county, we analyzed the data by BioNumerics 6.6 software. Results The DFR-type of Y. pestis in Xinlong county was same as DFR-type of other counties, all belonging to Genomovar05 type, but different from DFR-type of Shiqu county strains. Conclusion Genotype of Y. pestis isolated from Xinlong county is Genomovar05 type, and Xinlong plague natural foci is the part of Marmota himalayana plague natural foci of Tibetan Plateau.
QI Teng, LIANG Ying, YANG Jun, LUO Long-ze, LI Fan, WANG Li-mao, LI Wei
. Study on different region genotyping for Yersinia pestis of Xinlong county in Sichuan province[J]. Chinese Journal of Vector Biology and Control, 2018
, 29(5)
: 442
-444
.
DOI: 10.11853/j.issn.1003.8280.2018.05.005
[1] 祁腾,杨孔,汪立茂,等. 石渠县2001-2013年鼠疫疫源地流行病学分析[J]. 中国人兽共患病学报,2015,31(5):485-488. DOI:10.3969/cjz.j.issn.1002-2694.2015.05.020.
[2] 刘振才,海荣,李福忠,等. 青藏高原青海田鼠鼠疫自然疫源地的发现与研究[J]. 中国地方病学杂志,2001,16(6):321-327. DOI:10.3969/j.issn.1001-1889.2001.06.001.
[3] 祁腾,杨孔,汪立茂. 德格县2007-2012年动物间鼠疫流行病学调查[J]. 中国公共卫生,2014,30(2):178-181. DOI:10.11847/zgggws2014-30-02-16.
[4] Li YJ,Dai EH,Cui YJ,et al. Different region analysis for genotyping Yersinia pestis isolates from China[J]. PLoS One,2008,3(5):e2166. DOI:10.1371/journal.pone.0002166.
[5] 杨晓燕,魏柏青,辛友全,等. 青海高原鼠疫菌DFR分型及空间分布特征的研究[J]. 中国人兽共患病学报,2014,30(4):387-389,396. DOI:10.3969/cjz.j.issn.1002-2694.2014.04.009.
[6] 杨晓燕,魏柏青,靳娟,等. 中国鼠疫耶尔森菌差异区段分型及其地理分布特征[J]. 中华流行病学杂志,2014,35(8):943-948. DOI:10.3760/cma.j.issn.0254-6450.2014.08.015.
[7] Zhou DS,Han YP,Song YJ,et al. DNA microarray analysis of genome dynamics in Yersinia pestis:insights into bacterial genome microevolution and niche adaptation[J]. J Bacteriol,2004,186(15):5138-5146. DOI:10.1128/JB.186.15.5138-5146. 2004.
[8] 付秀萍,俞东征,海荣. 串联重复序列及其在鼠疫菌基因分型中的应用[J]. 中华流行病学杂志,2004,25(3):269-272. DOI:10.3760/j.issn:0254-6450.2004.03.022.
[9] 张蓉. 鼠疫菌MLVA分型技术及其应用[J]. 中华地方病学杂志,2013,32(2):234-236. DOI:10.3760/cma.j.issn.2095-4255. 2013.02.032.
[10] 杨瑞馥. 基因分析技术在鼠疫耶尔森菌中的应用[J]. 中华预防医学杂志,2015,49(1):1-2. DOI:10.3760/cma.j.issn.0253-9624.2015.01.001.
