At the initial stage of epidemics, the bacteria of plague natural foci were more virulent, nitrogen removal was stable, and the plasmid species were relatively complete and stable. But at the end of the epidemic, the virulence of the plague was weaker, nitrogen removal was not stable, and plasmids tended to be absent. There were great differences in the morphology of plague bacteria in nature. Biological, biochemical, plasmid and virulence of Yersinia pestis were investigated in Hebei province, China. The mechanism of the existence of plague was revealed in some way.
SHI Xian-ming, DU Guo-yi, WANG Zhi-yu, YANG Shun-lin, WANG Hai-feng, ZHOU Song, LIU Guan-chun, XIE Shu-jun, YAO Jian-kun, CUI Shu-xue, YANG Jian-ming, ZHANG Yi-hui
. Study on variability of Yersinia pestis in plague natural foci of Hebei province, China[J]. Chinese Journal of Vector Biology and Control, 2018
, 29(1)
: 100
-102
.
DOI: 10.11853/j.issn.1003.8280.2018.01.027
[1] 宋东霞,史献明,孔祥骊,等. 河北省鼠疫自然疫源地的发现及其防治对策的研究[J]. 中国媒介生物学及控制杂志, 1996,7(1):51-56.
[2] 王海峰,杜国义,史献明,等. 河北省鼠疫自然疫源地鼠疫菌生物学特征的研究概述[J]. 中国媒介生物学及控制杂志, 2010,21(6):638-639.
[3] 杨顺林,史献明,董国润,等. PCR用于鼠疫陈旧脏器标本检测的分析[J]. 疾病预防控制通报,2011,26(5):13-14,25.
[4] 董国润,李敬海,王桂琴,等. 冻干保存鼠疫菌的某些生物学特性研究[J]. 中国媒介生物学及控制杂志,1993,4(3):212-214.
[5] 杜国义,史献明,董国润,等. 鼠疫血清学研究进展[J]. 中国媒介生物学及控制杂志,2009,20(1):91-92,94.
[6] 祁芝珍,金丽霞,于晓涛,等. 我国鼠疫菌毒力因子的比较与分析[J]. 中华微生物学和免疫学杂志,2001,21(4):385-388.
[7] 刘满福,刘合智,张彩虹. 河北省鼠疫自然疫源地内啮齿动物种类及其分布的调查[J]. 中国媒介生物学及控制杂志, 2002,13(4):260-262.
[8] 刘秀莲. 河北省鼠疫菌毒力决定因子的变异[J]. 中国地方病防治杂志,1989,4(4):241.
[9] 刘秀莲,张月枝,白小英. 河北省鼠疫菌株的鉴定[J]. 中国地方病防治杂志,2002,17(2):103-104.
[10] 纪树立,张海峻,刘云鹏,等. 我国鼠疫菌分型及其生态学、流行病学意义[J]. 中国地方病学杂志,1982,6(5):257-262.
[11] 刘合智,张月芝,史献明,等. 河北省鼠疫菌株生化特性的研究[J]. 中国媒介生物学及控制杂志,2005,16(4):308-310.
[12] 李敬海,王福. 培基保存的鼠疫菌获得脱氮能力的报告[J]. 中国地方病防治杂志,1988,3(3):187-188.
[13] 刘合智,杜国义,白雪薇,等. 河北省鼠疫耶尔森菌毒力测定[J]. 中国地方病学杂志,2007,26(5):478-480.
[14] 杜国义,史献明,刘合智,等. 河北省鄂尔多斯高原型鼠疫菌毒力试验[J]. 地方病通报,2007,22(2):14-15.
[15] 徐菲莉,杨子平,李蕾,等. 新疆鼠疫自然疫源地鼠疫菌质粒图谱分析[J]. 地方病通报,1997,12(1):12-15.
[16] 董兴齐,彭何碧,叶枫,等. 云南省鼠疫疫源地鼠疫菌质粒DNA种类及分子流行病学研究[J]. 地方病通报,1994,9(4):58-63.
[17] 韩岳,王希良,董梅,等. tPA信号肽和鼠疫杆菌保护性抗原V融合基因的构建及免疫效果鉴定[J]. 现代免疫学,2006,26(6):477-482.
