Objective To investigate the density and population distribution of small mammals and provide the scientific basis for the small mammal control in the new tourist area of Shenzhen city. Methods The cage trapping method was used to monitor small mammals in Dapeng district from March 2016 to February 2017. The small mammal density and composition ratio were calculated, and the enumeration data were analyzed by chi-square test. Results A total of 559 small mammals were caught, with Suncus murinus being the predominant species accounting for 48.30%, followed by Rattus norvegicus accounting for 25.22%. The average density of small mammals was 7.25%, and the seasonal fluctuation was obvious(1.72%-11.93%), with the peak period from August to October. The small mammal density varied with different habitats, the highest density(11.35%)was in the old houses. Conclusion The small mammal density in the new tourist area was relatively high. So, it should be strengthened to prevent and control the small mammals. Suncus murinus, R. norvegicus, and R. tanezumi are the main vectors of concern.