Objective The discharge dynamic models of Gasterophilus spp. larvae were established by fitting the number of larvaeshedding from the equids after taking ivermectin. According to the models, the peaks of larvae discharge were predicted, which could help the collection of fresh maggots. Methods Three domestic horses and three Przewalski's horses were randomly selected and were kept in small enclosures separately. Maggots of each animal was harvested per unit time after taking ivermectin, the average rates of discharge larvae were calculated for both domestic and Przewalski's horses. Quadratic, Compound and Cubic models were used to fit the dynamics of larvae discharge. Results Among the three fitting models, the Cubic models were the best models to fit the discharge rate of the larvae (domestic horses:adjusted R2=0.837; Przewalski's horses:adjusted R2=0.940). The regression equations of the dynamic fitting of domestic and Przewalski's horses were:Yd=-1.302 766+0.075 436t-0.001 177t2+0.000 006t3 (27.6 ≤ t ≤ 87.9), Yp=-1.178 999+0.071 902t-0.001 157t2+0.000 006t3 (25.7 ≤ t ≤ 84.7). According to the regression equations, the peak values of domestic and Przewalski's horses were 49.0 h and 47.1 h. Conclusion The efficacy was not related to the equine species and infection intensity of Gasterophilus spp. larvae. The regression equation quantified the early observations, the conclusion could help to improve the collection efficiency and obtain fresh maggot samples, which laid a foundation for further study.
JIN Dong-mei, HUANG He-qing, BU Lan, WANG Zhen-biao, ZHANG Dong, LIU Shan-hui, LI Kai
. Study on the discharge dynamics of Gasterophilus spp.larvae after administration of ivermectin[J]. Chinese Journal of Vector Biology and Control, 2017
, 28(4)
: 318
-321
.
DOI: 10.11853/j.issn.1003.8280.2017.04.004
[1] Liu SH, Li K, Hu DF. The incidence and species composition of Gasterophilus (Diptera:Gasterophilidae) causing equine myiasis in northern Xinjiang, China[J]. Vet Parasitol,2016,217:36-38.
[2] Huang H, Zhang B, Chu H, et al. Gasterophilus (Diptera:Gasterophilidae) infestation of equids in the Kalamaili nature reserve, China[J]. Parasite,2016,23(4):36.
[3] 吴中兴,钱益新. 伊维菌素的药效、药理和临床研究[J]. 热带病与寄生虫学,2003,1(3):184-187.
[4] 吴仲达,李光裕,程霞,等. 伊维菌素的驱虫应用研究进展[J]. 兽药与饲料添加剂,2002,7(2):21-23.
[5] 陈进军,房文红,王松刚. 阿维菌素对水生动物安全性及其对寄生虫驱杀作用[J]. 科学养鱼,2015,31(2):90.
[6] Lourencao BC, Medeiros RA, Thomasi SS, et al. Amperometric flow-injection determination of the anthelmintic drugs ivermectin and levamisole using electrochemically pretreated boron-doped diamond electrodes[J]. Sensor Actuat B Chem,2016,222:181-189.
[7] Toguchi M, Chinone S. Evaluation of the efficacy of oral paste formulations of ivermectin against gastrointestinal parasites in horses[J]. J Equine Sci,2005,16(4):105-110.
[8] Fangama MI, Seri HI, Suliman SE, et al. Comparative efficacy evaluation of Moxidectin and ivermectin injectable formulation against helminthes infestation of donkeys (Equus asinus) in Sudan[J]. Assiut Vet Med J,2013,59(137):1-8.
[9] 张赫凡. 伊维速克对普氏野马寄生虫的驱虫效果[J]. 野生动物,2006,27(3):49,48.
[10] 刘善辉. 马胃蝇形态学、流行病学调查及线粒体COⅠ、16S rRNA系统发育研究[D]. 北京:北京林业大学,2012.
[11] 张赫凡,李凯,陈金良,等. 普氏野马寄生虫的监测[J]. 新疆师范大学学报:自然科学版,2008,27(1):94-96.
[12] 岳城,韩恿,曹洪明,等. 伊力佳对普氏野马寄生虫的驱虫效果分析[J]. 中国兽医杂志,2001,37(7):15.
[13] 高迎春. 动物科学用药[M]. 北京:中国农业出版社,2002:15-16.
[14] 卢纹岱. SPSS for Windows统计分析[M]. 3版. 北京:电子工业出版社,2006:312-313.
[15] 王文婷,肖洒,黄河清,等. 我国蒙新区、青藏区马胃蝇多样性及感染分析[J]. 林业科学,2016,52(2):134-139.
[16] 杨健梅,张东,胡德夫,等. 马胃蝇蛆病造成马体损伤性研究[J]. 中国畜牧兽医,2013,40(5):177-180.
