Objective To investigation the plague health education methods and content to meet the need of different people in Kangbao county of Hebei province, and lay a solid foundation for targeted health education and achieve better results. Methods An anonymous questionnaire was conducted to investigate 387 residents in Kangbao county. Results The targeted group's lower rates of knowing were "the treatment of sudden high fever after contact the plague animals or bite with flea"(8.56%), "Kangbao county is the plague natural foci"(20.72%), and "the symptoms of the plague patients"(28.45%). Different occupations need different ways of plague health education(χ²=105.118, P<0.01). Correspondence analysis found that farmers and broadcast,students and lectures, workers and broadcast, cadres and the micro-channel all have strong correlations. The 76.14% of farmers choose broadcast, 66.30% of students choose lectures, and the doctors prefer brochure(37.10%) and TV(37.10%). In addition to the panels, newspapers and text message, the workers like other publicities. The leaders like the other publicities except the panels. Conclusion Use radio and television primarily to strengthen the propaganda for farmers. Organize more health education lectures in school for students. For workers and cadres, take a variety of ways of health education, for example, broadcasting, WeChat and text message. Doctors, considering the professional particularity, should be trained and assessed professionally to improve their emergency relief capability.