Objective To investigate the distribution of Aedes albopictus in the central city of Yuxi, providing scientific basis for prevention and control of dengue fever. Methods Mosquito larvae were captured indoor and outdoor water containers from north, south, west, east and central residential areas and special places in the central city; adult mosquito was collected by human landing collection and whole site at special places; and dengue virus was tested by specific nucleic acid detection for Ae. albopictus adult mosquitoes. Results Aedes albopictus was found in 3 villages at the north of the city and 1 residential area at the west of the city,the total container index(CI) was 0.37. In the east, south and center of the city, no Ae. albopictus was found. Total of 2 193 individuals of 7 species were collected from a waste tire processing factory and a salvage station in the north and west of the city, and Ae. albopictus accounted for 82.44%(1 808/2 193); the CI of larvae was 5.21, Breteau index reached up to 60.00 at waste tire processing factory in the north of the city. No dengue virus was detected in Ae. albopictus adult mosquitoes. Conclusion It was the first time found Ae. albopictus in the central city of Yuxi, and its density was high, it's hinted that there is a risk of dengue transmission and epidemic, and the attention should be paid by the relevant health departments.