Objective To analyze malaria surveillance data of Yuanjiang county of Yunnan from 1995 to 2012. Methods Data were collected from Yuanjiang county during 1995 to 2014, including malaria cases, number of resident and mobile population febrile patient blood screening, resident malaria parasitic rate, vector population density and the other data;of those malaria case was identified by tradition microscope method, malaria vector density was investigated by human hour collection mosquito in resident houses or animal shelters, and human infected malaria antibody level was tested by indirect fluorescence antibody test. Results During 1995 to 2014, total of 6 986 malaria cases were reported, in those years the highest malaria morbidity were in 1995 (84.07/10 000, 1 531 cases) and the lowest in 2012 (0 cases); total of 209 824 febrile resident patient bloods were screened, its malaria positive rate was 3.41%; total of 26 373 mobile population febrile patient bloods were tested, its malaria positive rate was 7.65%; total of 51 540 healthy residents were investigated for malaria parasite, its positive rate was 1.56%; the indirect fluorescent antibody positive rate of malaria was 39.34%(769/1 955)in 1997 but 0(0/320) in 2012; Anopheles minimus population density declined rapidly from 1995 to 2014, in consistence with annual malaria morbidity, while that of An. sinensis declined during 1995 to 2002, but increased gradually since 2002. Conclusion Above malaria monitor results suggested that imported malaria case management of mobile population and vector monitor were needed to strengthen, in order to avoid local transmissions causing by imported cases.