Investigation on tick?borne Rickettsia and its coinfections in rodents collected in forest area in the Northeastern China

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  • 1 Center of Disease Prevent and Control of Shenyang Command, Shenyang 110034, Liaoning Province, China;
    2 Department of Clinical laboratory, No. 463 Hospital of PLA, Shenyang 110042, Liaoning Province, China;
    3 PLA 65755 Military Medical Team

Received date: 2015-04-22

  Online published: 2015-10-20

Supported by

Supported by the Major National Science and Technology Projects of China (No. 2013ZX10004-203) and the Project of Applied Basic Reseach (No. AWS11L009)

Abstract

Objective To study the existence of human granulocytic anaplasmosis (HGA), human monocytic ehrlichiosis (HME) and tick-borne spotted fever (SF) in rodents in northeastern China. Methods Using polymerase chain reaction (PCR), Anaplasma (Ap), Ehrlichia (Ec) and spotted fever group rickettsiae (SFGR) were detected in rodent samples collected from Ji’an of Jilin province and kuandian of Liaoning province. Results In 132 wild rodent, 66 collected from Ji’an, Ap and Ec and SFGR were detected positive, with rates as 7.58%, respectively. 66 collected from kuandian, Ap and Ec and SFGR were detected positive, with rates as 21.21%, 4.55%, 13.64%, respectively. 3(2.27%) were coinfections with Ec and Ap, while 2(1.52%) was coinfections with Ec and SFGR. There was no coinfections of Ap and SFGR. Conclusion There exists natural foci of Ap, Ec and SFGR in the investigated area. Coinfections of Ec and Ap or Ec and SFGR did exist in rodents in Changbai mountain area, China.

Cite this article

WANG Zhuo, WANG Rong, ZHOU De-zhuang, YANG Yi-jun, YU Miao, WANG Feng, FENG Li, WU Yi-min . Investigation on tick?borne Rickettsia and its coinfections in rodents collected in forest area in the Northeastern China[J]. Chinese Journal of Vector Biology and Control, 2015 , 26(5) : 467 -470 . DOI: 10.11853/j.issn.1003.4692.2015.05.009

References

[1] Centers for Disease Control and Prevention. Tick-borne Rickettsial diseases[DB/OL]. (2008-12-20)[2014-12-25]. http://www.cdc.gov/ticks/index.html.
[2] Walker DH, Paddock CD, Dumler JS. Emerging and re-emerging tick-transmitted rickettsial and ehrlichial infections[J]. Med Clinics North Am, 2008, 92(6):1345-1361.
[3] Kim CM, Yi YH, Yu DH, et al. Tick-borne Rickettsial pathogens in ticks and small mammals in Korea[J]. Appl Environ Microbiol, 2006, 72(9):5766-5776.
[4] Zhang LJ, Liu Y, Ni DX, et al. Nosocomial transmission of human granulocytic anaplasmosis in China[J]. JAMA, 2008, 300(19):2263-2270.
[5] Lin Z, Wu CC, Chen YC, et al. Tick-borne agents in rodents, China, 2004-2006[J]. Emerg Infec Dis, 2009, 15(12):1904-1908.
[6] Zhang LJ, Liu H, Xu BL, et al. Anaplasma phagocytophilum infection in domestic animals in ten provinces/cities of China[J]. Am J Trop Med Hyg, 2012, 87(1):185-189.
[7] Zhang LJ, Wang GQ, Liu QH, et al. Molecular analysis of Anaplasma phagocytophilum isolated from patients with febrile diseases of unknown etiology in China[J]. PLoS One, 2013, 8(2):e57155.
[8] Ismail N, Bloch KC, McBride JW. Human ehrlichiosis and anaplasmosis[J]. Clinics Lab Med, 2010, 30(1):261-292.
[9] 赵庆亮, 黄林, 杨霞, 等. 新疆部分地区鼠类无形体和埃立克体的调查及16S rRNA序列分析[J]. 中国人兽共患病学报, 2013, 29(8):743-747.
[10] 高玉敏, 张习坦, 曹务春, 等. 用半套式PCR检测蜱和啮齿动物中查菲埃立克体[J]. 中国人兽共患病杂志, 2000, 16(3): 25-28.
[11] 柴程良, 孙继民, 陆群英, 等. 浙江省鼠形动物蜱源立克次体感染状况调查[J]. 浙江预防医学, 2014, 26(7):659-663.
[12] Wimberly MC, Yabsley MJ, Baer AD, et al. Spatial heterogeneity of climate and land-cover constraints on distributions of tick-borne pathogens[J]. Global Ecol Biogeogr, 2008, 17(2):189-202.
[13] Lin Z, Wu CC, Jia FJ, et al. Anaplasma phagocytophilum in livestock and small rodents[J]. Veterin Microbiol, 2010, 144(3/4):405-408.
[14] 孙毅, 刘国平, 杨丽炜, 等. 黑龙江省部分林区全沟硬蜱复合感染重要蜱媒病原的调查研究[J]. 寄生虫与医学昆虫学报, 2007, 14(4):231-240.
[15] Dong X, Chen XP, Liu N, et al. Co-circulation of multiple species of Rickettsiales bacteria in one single species of hard ticks in Shenyang, China[J]. Ticks Tick Borne Dis, 2014, 5(6):727-733.
[16] 吴琼, 冯立, 王洪军, 等. 东北部分地区蜱携带几种病原立克次体的分子检测[J]. 中国预防医学杂志, 2012, 13(12):892-894.

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