ISSN 1003-8280 CN 10-1522/R 中国疾病预防控制中心 主办
Chinese Journal of Vector Biology and Control >
Investigation and analysis on the transmission of severe fever with thrombocytopenia syndrome via contact with patient
Received date: 2014-10-21
Online published: 2015-04-20
Supported by
Supported by the Zhejiang Province Public Technology Application of Fund(No. 2012C33063)and the Medical Research Program of Zhejiang Province(No. 2014RCA002)
Objective To investigate the infection source of severe fever with thrombocytopenia syndrome (SFTS) cases and provide the scientific information for control and prevention of SFTS. Methods The clinical and epidemiological history for 2 cases was investigated and the host animals (rat, sheep, dog) and tick were monitored. The rodent liver and spleen specimens and ticks were detected by fluorescence quantitative PCR, and the rat shape animal serum and goat serum antibody was detected by ELISA. Results Case B was diagnosed as mild case based on clinical symptom and pathogen detection results. Epidemiological investigation showed that case A had no tick exposure history, probably infected during the nursing period. Serological investigation of the results showed that the village had previous or recessive infection. And the domestic and wild animal (rat) in this village carried ticks. All the results hint that this village was novel bunyavirus natural focus. Conclusion Severe fever with thrombocytopenia syndrome can spread through contact. Close contact patients should strengthen individual protection.
HUANG Wen-zhong, YU Xiang-hua, WU Hong-zhao, ZHANG Lei, MIAO Zi-ping, LYU Hua-kun . Investigation and analysis on the transmission of severe fever with thrombocytopenia syndrome via contact with patient[J]. Chinese Journal of Vector Biology and Control, 2015 , 26(2) : 172 -175 . DOI: 10.11853/j.issn.1003.4692.2015.02.016
[1] Yu XJ, Liang MF, Zhang SY, et al. Fever with thrombocytopenia associated with a novel bunyavirus in China[J]. N Engl J Med,2011, 364(16):1523-1532.
[2] 汪金生. 发热伴血小板减少综合征研究进展[J]. 安徽预防医 学杂志, 2012, 18(4):281-284.
[3] 刘力, 官旭华, 邢学森, 等. 2010年湖北省发热伴血小板减少 综合征的流行病学分析[J]. 中华流行病学杂志, 2012, 33 (2):168-172.
[4] Bao CJ, Qi X, Wang H. A novel Bunyavirus in China[J]. N Engl J Med, 2011, 365(15):862-863.
[5] 曲荣波, 郭祝宽, 秦秀燕. 荣成市一起聚集性发热伴血小板减 少综合征疫情流行病学调查[J]. 热带医学杂志, 2013, 13 (10):1289-1291.
[6] 陶文元, 陶欣. 新型布尼亚病毒感染致发热伴血小板减少综 合征8 例报告[J]. 江苏大学学报:医学版, 2011, 21(1): 91-92.
[7] 林桂仁, 杨霞, 于铭. 一起聚集性发热伴血小板减少综合征4 例报告[J]. 求医问药, 2012, 10(7):741.
[8] Bao CJ, Guo XL, Qi X, et al. A family cluster of infections by a newly recognized Bunyavirus in eastern China, 2007:further evidence of person-to-person transmission[J]. Clin Infect Dis,2011, 53(12):1208-1214.
[9] Sun JM, Chai CL, Lv HK, et al. Epidemiological characteristics of severe fever with thrombocytopenia syndrome in Zhejiang province, China[J]. Inter J Infect Dis, 2014, 25:180-185.
[10] Sun JM, Zhang YJ, Gong ZY, et al. Seroprevalence of severe fever with thrombocytopenia syndrome virus in southeastern China and analysis of risk factors[J]. Epidemiol Infec, 2014. doi:10.1017/S0950268814001319.
[11] Gai ZT, Liang MF, Zhang Y, et al. Person to person transmission of severe fever with thrombocytopenia syndrome Bunyavirus through blood contact[J]. Clin Infect Dis, 2012, 54(2): 249-252.
[12] Liu Y, Li Q, Hu WF, et al. Person-to-person transmission of severe fever with thrombocytopenia syndrome virus[J]. Vector Borne Zoonot Dis, 2012, 12(2):156-160.
[13] Tang XY, Wu WL, Wang HF,et al. Human-to-human transmission of severe fever with thrombocytopenia syndrome Bunyavirus through contact with infectious blood[J]. J Infect Dis, 2013, 207(5):736-739.
[14] Chen HB, Hu K, Zou JJ, et al. A cluster of cases of human-to- human transmission caused by severe fever with thrombocytopenia syndrome Bunyavirus[J]. Inter J Infect Dis,2013, 17(3):206-208.
[15] 练祥, 陈晨松, 柯婷婷, 等. 宁波地区2 例发热伴血小板减少综 合征患者的临床特征[J]. 疾病监测, 2013, 28(1):13-16.
[16] 王素云, 沈春莲, 吴丽花, 等. 新型布尼亚病毒感染3例[J]. 中 国乡村医药杂志, 2013, 20(3):43-44.
[17] 顾全忠, 王玉超, 蒲柳艳, 等. 舟山地区新型布尼亚病毒感染 致发热伴血小板减少综合征6例流行特征[J]. 国际流行病学 传染病学杂志, 2012, 39(5):348-349.
[18] 叶凌, 任宜, 王忠发. 舟山海岛地区2011－2012年新型布尼亚 病毒感染监测分析[J]. 中国媒介生物学及控制杂志, 2013,24(5):429-431.
[19] Liu SL, Chai CL, Wang CM, et al. Systematic review of severe fever with thrombocytopenia syndrome:virology, epidemiology,and clinical characteristics[J]. Rev Med Virol, 2014, 24(2): 90-102.
[20] 叶凌, 任宜, 毛彬, 等. 一起家庭聚集性新布尼亚病毒感染病 例的报道[J]. 疾病监测, 2012, 27(12):987-989.
[21] 袁春, 崔宁, 王炳军, 等. 253 例发热伴血小板减少综合征的临 床表现特征[J]. 中国现代医学杂志, 2011, 21(27): 3413-3417.
/
| 〈 |
|
〉 |