Abstract: Objective To analyze the relationship between Demodex infection and individual hygienic habits. Methods A computer-based online search of reports from 1994 to 2006 was conducted in literatures and Chinese database of Biology and Medicine, and all literatures related to the Demodex infection and individual hygienic habits were recorded, registered and statistically analyzed. Results A total of 11 literatures were selected to analyze the relationship between Demodex infection and individual hygienic habits. There were totally 9356 cases included. The infection rate of Demodex of people who have habit of mixed using special facecloth and washbasin is 45.82%, the others' is 27.71% in the study. The former is significantly higher than the latter and yielded the summary OR of 2.49, and the 95 percent confidence interval (95%CI) is 1.94 to 3.20. 3230 cases in 7 province were selected to deduce the relationship between the infection rate of Demodex and skin cleaning article. Comparing the infection rate of Demodex of people who often use skin cleanser with those who use rarely, the former is 27.25% and the latter is 31.44% and yielded the summary OR of 0.70, and the 95%CI is 0.52 to 0.93. Conclusion There is some relevance between Demodex infection and individual hygienic habits in Chinese mainland. Evidence suggested that the habit of mixing use of facecloth and washbasin is a risk factor of Demodex infection, while using of skin cleanser is a protective factor.

摘要： 目的 探讨人体蠕形螨感染与个人卫生习惯的关系。方法 采用Meta分析方法对1994年1月1日至2006年12月31日在中国期刊网上检索到的有关混用生活用品者和使用洁面用品者与蠕形螨感染关系的文献进行综合定量评价。结果 检索到有关生活用品混用的文献11篇,累计调查人数为9356人,其中经常混用生活用品者5447人,蠕形螨平均感染率为45.82%;不常混用生活用品者3909人,蠕形螨平均感染率为27.71%,二者间的差异有统计学意义(χ²=316.28,P<0.05),生活用品混用者蠕形螨感染率明显高于不混用者,OR_合并为2.49,95%可信区间(95%CI)为[1.94,3.20]。检索到符合使用洁面用品纳入标准的相关文献7篇,总调查人数3230人,其中纳入不使用洁面用品者1476人,蠕形螨的平均感染率为31.44%;使用洁面用品者1754人,蠕形螨的平均感染率为27.25%,二者之间的差异亦有统计学意义(χ²=6.79,P<0.05),经常使用洁面用品者蠕形螨的感染率显著低于不常使用洁面用品者,OR合并为0.70,95%CI为[0.52,0.93]。结论 人体蠕形螨感染与个人卫生习惯有一定的关联性,混用生活用品是蠕形螨感染的危险因素,而使用洁面用品则是蠕形螨感染的保护因素。

关键词: 人体蠕形螨, 感染率, 卫生习惯, Meta分析