ISSN 1003-8280 CN 10-1522/R 中国疾病预防控制中心 主办
Chines Journal of Vector Biology and Control
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LIANG Lian; DAI Guang-xiang; LI Yu-lian;et al
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梁练;戴广祥;李玉莲;胡杰;张世炎
Abstract: Objective To provide base data for Bromadiolone resistance monitoring in Rattus flavipectus,determined the susceptibility ofR.flavipectus to Bromadiolone.Methods Firstly hived off the males and females,then divided into groups at random.No-choice tests were carried out using the Bromadiolone bait at concentration of(0.000 3%) at six different feeding days.Using Bliss software,the relevant between death rates and the different feeding days were analysed statisties.Results There was no signicanty difference((Pb>)(0.05),P(LFP50)>(0.05)) between sex in the Bromadiolone susceptibility.The LF-P line was(y=2.85+3.69x.On combination of the sex data,LFP50 and LFP99 and its 95% fiducial limits forR.flavipectus were(3.81)((3.18-4.58),(16.26)(9.95-25.56) days respectively.Conclusion According to the revising rodent resistance diagnose of WHO,the localR.flavipectus fed the 0.000 3% the bait living for 17 days and above can be as the resistance diagnose.
摘要: 目的 测定黄胸鼠对抗凝血灭鼠剂溴敌隆的敏感性,为测定抗药性提供黄胸鼠敏感种群本底资料。方法 在实验室做无选择性摄食试验。将试鼠雌雄分开,随机分组,按6个不同食毒期摄食0.000 3%溴敌隆毒饵。用Bliss计算机程序,计算不同食毒期与对应死亡率之间的关系。结果 黄胸鼠性别之间对溴敌隆的敏感性差异无统计学意义(Pb>0.05,PLFP50>0.05),故雌雄数据合并计算,得毒力回归线y=2.85+3.69x,LFP50、LFP99及其95%置信限(95%CI)分别是3.81(3.18~4.58)、16.26(9.95~26.56)d。结论 按WHO修订以致死99%敏感靶标鼠种的食毒期(LFP99)取整天数作为抗药性检验标准,湛江地区黄胸鼠对0.000 3%的溴敌隆毒饵食毒期超过17 d存活为产生抗药性。
关键词: 黄胸鼠, 溴敌隆, 敏感性, 抗药性
LIANG Lian; DAI Guang-xiang; LI Yu-lian;et al. The Susceptibility of Rattus flavipectus to Bromadiolone[J]. Chines Journal of Vector Biology and Control.
梁练;戴广祥;李玉莲;胡杰;张世炎. 黄胸鼠对溴敌隆的敏感性研究[J]. 中国媒介生物学及控制杂志.
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