ISSN 1003-8280 CN 10-1522/R 中国疾病预防控制中心 主办
Chines Journal of Vector Biology and Control
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ZHU Hong-bin; CHEN Dong-ping; QIAN Wei-ping; et al
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朱鸿斌;陈东平;钱微萍;周忆昭;周静
Abstract: Objective:To study the repellent efficacy and acute toxicity of Meijie Wang Repellent.Methods:Laboratory experiments.Results:After human volunteer's hand and baby mice exposed to the repellent with the dosage of 0.063 ml/cm2,the experiment results indicated that effective repellent protection time against Culex pipiens quinquefasciatus was over 6 hours.The toxic experiment showed that the acute oral toxicity(LD50) to white rats was more than 5000 mg/kg.But it was slightly irritant to shin and eye.Conclusion:The repellent is good for repelling mosquito and low acute toxicity substance.
摘要: 目的:评价美洁王驱蚊露的驱蚊效果及其在使用中的安全性。方法:将美洁王驱蚊露涂抹于人或小白鼠的裸露皮肤上,进行驱避效果试验,判断其对人的有效保护时间;急性经口毒性试验采用一次性经口灌胃;急性皮肤刺激和眼刺激试验则直接涂药于家兔皮肤和滴药于眼结膜囊内。结果:美洁王驱蚊露对人的有效保护时间>6h;大鼠急性经口LD50>5000mg/kg;对家兔皮肤平均刺激指数为0.5;急性眼刺激积分指数为6。结论:美洁王驱蚊露对蚊虫有较好的驱避作用,且毒性低,使用安全,但对皮肤及眼有轻度刺激性。
关键词: 美洁王驱蚊露, 驱避效果, 急性毒性
ZHU Hong-bin; CHEN Dong-ping; QIAN Wei-ping; et al. Laboratory Evaluation of Efficacy and Safety of Meijie Wang Repellent[J]. Chines Journal of Vector Biology and Control.
朱鸿斌;陈东平;钱微萍;周忆昭;周静. 美洁王驱蚊露驱蚊效果及其安全性评价[J]. 中国媒介生物学及控制杂志.
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