ISSN 1003-8280 CN 10-1522/R 中国疾病预防控制中心 主办
Chines Journal of Vector Biology and Control
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ZHOU Li-qiang; CHEN Su-liang; GUO Yi-xiu; et al
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周立强;陈素良;郭逸秀;师鉴;关文英;李桂银;张亚利;甄素娟
Abstract: Objective:To study infection state of Richettsia tsutsugamushi(Rt) among mouse host in epidemic focus in Hebei province.Methods:Following items were carried out:to catch mice in epidemic village and field(catch-mouse),observe abnormal phenomena of liver and spleen,inoculate liver and spleen samples to small white mouse with Kunming species(experimental mouse),smear and/or freeze cut section of liver and spleen from experimental mouse to detect Rt,take blood specimens from catch-mouse and experimental mouse to test antibodies against Rt with IFA.Results:In the different species mice caught,the rate of hepatomegaly and/or splenomegaly were from 60% to 100%,and prevalance of Rt antibody were from 0% to 50%.In the experimental mouse with inoculation liver and spleen samples came from different species mice caught,incidence of the disease were from 96.23% to 100%,smear positive rate of Rt were 25% to 50%,9 of 10 freezing cut section samples were Rt positive,the positive rate of Rt antibodies of experimental mouse sera came from Rattus norvegicusit was 9.52%.Conclusion:Transmissible hosts in the residence area are Rattus norvegicusit,and in the field are Cricetulus triton and Apodemus agrarius.
摘要: 目的:了解河北省某恙虫病疫源地鼠宿主的感染状况,确定恙虫病传播宿主。方法:捕捉疫村内及疫村周围鼠,采集血标本检测恙虫病立克次体的荧光抗体,解剖观察肝脾肿大情况,采集肝脾标本接种昆明种小白鼠,观察传代鼠的发病情况,涂片或切片检测其肝脾中恙虫病立克次体,检测其血清中的荧光抗体。结果:不同鼠肝脾肿大率为60%~100%,鼠的恙虫病抗体流行率为0%~50%,传代鼠的发病率为96.23%~100%,传代鼠的肝脾涂片Rt阳性率为25%~50%,仅在褐家鼠肝脾的传代鼠血清中查到抗体,阳性率为9.52%。10份肝脾切片中9份检出Rt。结论:宅区褐家鼠、野外大仓鼠和黑线姬鼠为当地恙虫病传播宿主。
关键词: 恙虫病, 传播宿主, 动物实验
ZHOU Li-qiang; CHEN Su-liang; GUO Yi-xiu; et al. Study on Infection of Richettsia Tsutsugamushi among Mouse Hostina Epidemic focus,Hebei province[J]. Chines Journal of Vector Biology and Control.
周立强;陈素良;郭逸秀;师鉴;关文英;李桂银;张亚利;甄素娟. 河北省某恙虫病疫源地鼠宿主感染的研究[J]. 中国媒介生物学及控制杂志.
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