Abstract: In 1995～1997, we conducted seroepidemiological survey of Lyme disease in Hubei province. Bymeans of ELISA the sera of 1 162 forest residents were tested for antibodies against Borrelia burgdorferi strain FP₁ isolated from a patients with facial paralysis, 122(10.49%) residents had significant IgG titers, including 57 ( 14.39 %) from Wufeng county, 37( 9.92 %) from Nanzhang county, and 28( 7.12 %) from Baotang county. It was confirmed that there are infections of Lyme disease among the forest residents in Hubei province.

摘要： 目的：查明湖北省人群莱姆病感染情况。方法：间接酶联免疫吸附试验、莱姆病血清流行病学调查。结果：从1192人中检出阳性152份，排除钩体MAT阳性30份，实际莱姆病IgG抗体阳性122份，阳性率10．49％（122／1162）。其中五峰县14．39％，南漳县9．92％，保康县7．12％。男性阳性率10．71％，女性阳性率9．94％，性别间差异无显著性。人群年龄为9～68岁，20～40岁青壮年感染阳性率最高。不同职业人群感染率，农民8．93％，林业工人13．65％，学生3．57％。人群蜱叮咬率为5．92％。有蜱叮咬史者莱姆病阳性率高达56．71％；而无明确蜱叮咬史者阳性率仅为7．67％。确诊莱姆病关节炎4例。结论：湖北省人群中有莱姆病的感染存在，并有莱姆病发生。

关键词: 莱姆病, 血清流行病学