Abstract: In 1991～1992, the sera of 87s forest residents in Huaihua prefecture of Hunan were tested for antibodies against borrelia (Strain B31) by IFA. 62 (7.09%) of forestry residents had significant IgG titers(1: 128). 43(4.91%) cases were confirmed being Lyme disease by serological and clinical examination. Borrelia burgdorferi was isolated from the kidney and bladder of Gaprolagus sinensis in Huaihua. This result shows that Caprolagus sinensis may be important reservoirs for Lyme disease spirochete in south region of Hunan. This is a first report that Lyme disease apirocbete was isolated from Caprolagus sinensis in the world.

摘要： 作者于1991～1992年在湖南省怀化地区进行了莱姆病调查,首次证实该地区存在莱姆病自然疫源地。对怀化所属6个县(市)的875名林区居民进行了调查,抗莱姆病螺旋体血清抗体(IgG)阳性者62例,感染率为7.09%。经临床和血清学检测,确诊莱姆病患者43例,患病率为4.91%。临床表现有环形或游走性红斑(ECM)、关节炎、慢性脑膜炎、面神经麻痹、多发性神经炎和心脏损害等多种类型。从野兔(华南兔)体内分离出1株莱姆病螺旋体,这在国内外属首次报道。

关键词: 莱姆病, 慢性游走性红斑, 莱姆病螺旋体, 华南兔