Abstract: Objective To investigate the resistance level of Aedes albopictus against some commonly used insecticides in dengue endemic provinces of China, and to provide guidance for the proper usage of insecticides and epidemic prevention and control. Methods Excel 2016 software was used to collect and sum up the bioassay data of Ae. albopictus resistance to commonly used insecticides from 80 surveillance sites in 13 provinces in China. The WHO tube method was used to monitor the resistance of adult mosquitoes against 9 insecticides, and larval dip method was used to monitor the resistance of larvae mosquitoes against 3 insecticides. According to the Implementation Plan for National Vector Surveillance (2016), the resistance level was statistically analyzed and mapped using ArcGIS 10.3 software. Results The resistance of Ae. albopictus was monitored at 80 surveillance sites in China in 2020. For pyrethroid insecticides, Ae. albopictus adults developed resistance to deltamethrin, permethrin, beta-cypermethrin and beta-cyhalothrin at 83.08% (54/65), 77.97% (46/59), 87.30% (55/63),and 79.31% (46/58) of the surveillance sites, respectively. For carbamate insecticides, Ae. albopictus adults developed resistance to propoxur in 1.49% (1/67) sites, while none of the 61 sites showed resistance to bendiocarb. For organophosphorus insecticides, the Ae. albopictus adults at the 6.45% (4/62) surveillance sites developed resistance to malathion, while the 52 and 59 sites did not develop resistance to fenitrothion and chlorpyrifos. Ae. albopictus larvae at 93.48% (43/46), 28.30% (15/53), and 25.45% (14/55) of the sites showed medium or high resistance to pyriproxyfen, propoxur and temephos, respectively. Conclusion The resistance level of adult Ae. albopictus to pyrethroid insecticides and larva to pyriproxyfen were serious in dengue endemic and risk areas in China. However, both adult and larva were more susceptible to carbamate and organophosphorus insecticides at most of surveillance sites. Local authorities and program managers should adjust their insecticide use planning for Aedes mosquito control and dengue prevention and control according to the current insecticide resistance status.

Key words: Aedes albopictus, Surveillance, Insecticide, Insecticide resistance

摘要： 目的 了解我国登革热流行省份的媒介伊蚊对常用杀虫剂的抗药性水平，为各地的杀虫剂使用及疫情防控提供指导意见。方法 使用Excel 2016软件收集和整理来自我国13个省（自治区、直辖市）80个监测点的白纹伊蚊对常用杀虫剂的抗药性生物测定数据，其中使用接触筒法监测成蚊对9种杀虫剂的抗药性，使用幼虫浸渍法监测幼蚊对3种杀虫剂的抗药性，根据《全国病媒生物监测实施方案（2016）》统计分析其抗药性水平，使用ArcGIS 10.3软件绘制抗药性水平地图。结果 2020年对我国登革热流行省份共80个监测点进行了白纹伊蚊抗药性监测，结果显示分别有83.08%（54/65）、77.97%（46/59）、87.30%（55/63）和79.31%（46/58）的监测点的白纹伊蚊成蚊对溴氰菊酯、氯菊酯、高效氯氰菊酯、高效氯氟氰菊酯产生了抗药性；有1.49%（1/67）的监测点的白纹伊蚊成蚊对残杀威产生了抗药性，61个监测点的白纹伊蚊成蚊对虫威均未产生抗药性；有6.45%（4/62）的监测点的白纹伊蚊成蚊对马拉硫磷产生了抗药性，另52和59个监测点的白纹伊蚊成蚊对杀螟硫磷及毒死蜱均未产生抗药性。幼蚊监测结果显示，分别有93.48%（43/46）、28.30%（15/53）和25.45%（14/55）的监测点的白纹伊蚊幼蚊对吡丙醚、残杀威和双硫磷产生了中高抗药性。结论 我国登革热流行省份的白纹伊蚊成蚊对拟除虫菊酯类杀虫剂抗药性较为严重，对氨基甲酸酯类和有机磷类杀虫剂抗药性水平较低；幼蚊对吡丙醚抗药性较为严重。各地应根据当地白纹伊蚊抗药性实际情况，调整杀虫剂使用方案，提高媒介伊蚊控制效果。

关键词: 白纹伊蚊, 监测, 杀虫剂, 抗药性