Blocking transmission of mosquito-borne diseases through population suppression using Wolbachia

doi:10.11853/j.issn.1003.8280.2020.01.024

Chines Journal of Vector Biology and Control ›› 2020, Vol. 31 ›› Issue (1): 113-116.DOI: 10.11853/j.issn.1003.8280.2020.01.024

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Blocking transmission of mosquito-borne diseases through population suppression using Wolbachia

YANG Cui^1,2, XI Zhi-yong^3,4, HU Zhi-yong^5,6

1 School of Economics and Statistics, Guangzhou University, Guangzhou 510530, Guangdong Province, China;
2 Guangzhou Wolbaki Biotech Co., Ltd.;
3 Sun Yat-sen University-Michigan State University Joint Center of Vector Control for Tropical Diseases, Key Laboratory for Tropical Disease Control, Ministry of Education;
4 Department of Microbiology and Molecular Genetics, Michigan State University, East Lansing, Michigan, USA;
5 Institute of Intelligent Finance, Accounting&Taxation, Guangzhou University;
6 Guangdong Engineering and Technology Research Center of Intelligent Finance, Accounting&Taxation

Received:2019-08-21 Online:2020-02-20 Published:2020-02-20
Supported by:
Supported by the Key Project of Chinese Ministry of Education (No. 311030), Guangdong Innovative Research Team Program (No. 2011S009), and the National Institutes of Health/National Institute for Allergy and Infectious Disease and the IAEA-TC project (No. RAS5066)

应用沃尔巴克氏体通过种群压制阻断蚊媒病传播的研究进展

杨翠^1,2, 奚志勇^3,4, 胡志勇^5,6

1 广州大学经济与统计学院, 广东广州 510530;
2 广州威佰昆生物科技有限公司, 广东广州 510530;
3 中山大学-密歇根州立大学热带病虫媒控制联合研究中心, 广东广州 510080;
4 美国密歇根州立大学微生物和分子遗传学系, 美国密歇根东兰辛 48824;
5 广州大学智慧金财税研究所, 广东广州 510006;
6 广东省智慧金财税工程技术研究中心, 广东广州 510006

通讯作者: 胡志勇,Email:zhyhu65@163.com
作者简介:杨翠,女,博士,从事利用沃尔巴克氏体进行种群压制的质量控制研究,Email:yangcui0413@163.com
基金资助:
教育部科学技术研究重点（重大）项目（311030）；广东省引进创新科研团队计划（2011S009）；国际原子能地区合作项目（RAS5066）

Abstract

Abstract: Over the last three decades, mosquitoes have been the major vector of dengue, malaria, and Zika virus infection. However, there are lack of reliable and effective drugs and vaccines for these infectious diseases. Traditional chemical control faces problems like insecticide resistance and environmental pollution. Thus, a new technique for mosquito control is desperately needed. Wolbachia induces cytoplasmic incompatibility and pathogen resistance in the host, which makes it feasible to achieve population suppression or even regional eradication of mosquito vectors. Through searching for and comprehensively analyzing domestic and international literature, this article reviews the principle of population suppression by Wolbachia and relevant laboratory and field research, so as to have a comprehensive understanding of research progress and problems in blocking transmission of mosquito-borne diseases through population suppression using Wolbachia.

Key words: Wolbachia, Mosquito vector, Population suppression

摘要： 在过去的30年间，蚊类已成为传播登革热、疟疾和寨卡病毒病的主要媒介，目前还没有可靠有效的药物和疫苗。传统的化学防治技术正面临着昆虫抗药性和环境污染等问题，亟需发展一种新型的蚊媒控制技术。沃尔巴克氏体（Wolbachia）能够诱导宿主产生胞质不相容性，并引起宿主对病原体的抗性，使得利用沃尔巴克氏体进行种群压制或区域性根除传病蚊媒成为可能。该文通过检索和综合分析国内外文献，从沃尔巴克氏体的种群压制原理、实验室和现场研究等几个方面进行综述，以全面了解利用沃尔巴克氏体通过种群压制阻断蚊媒病传播的研究进展和问题。

关键词: 沃尔巴克氏体, 蚊媒, 种群压制

CLC Number:

R376

YANG Cui, XI Zhi-yong, HU Zhi-yong. Blocking transmission of mosquito-borne diseases through population suppression using Wolbachia[J]. Chines Journal of Vector Biology and Control, 2020, 31(1): 113-116.

杨翠, 奚志勇, 胡志勇. 应用沃尔巴克氏体通过种群压制阻断蚊媒病传播的研究进展[J]. 中国媒介生物学及控制杂志, 2020, 31(1): 113-116.

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Blocking transmission of mosquito-borne diseases through population suppression using Wolbachia

应用沃尔巴克氏体通过种群压制阻断蚊媒病传播的研究进展

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