Chines Journal of Vector Biology and Control ›› 2013, Vol. 24 ›› Issue (6): 477-482.DOI: 10.11853/j.issn.1003.4692.2013.06.001

• Expert Forum •     Next Articles

Research advances on immune mechanism against pathogens in mosquitoes

WANG Yan-hong, WANG Ju-mei, JIANG Hong, ZOU Zhen   

  1. State Key Laboratory of Integrated Management of Pest Insects and Rodents, Institute of Zoology, Chinese Academy of Sciences, Beijing 100101, China
  • Received:2013-08-19 Online:2013-12-20 Published:2013-12-20
  • Supported by:

    Supported by the National Basic Research Program of China (973 Program) (No. 2014CB138400) and the National Natural Science Foundation of China (No. 31272367)


王燕红, 王举梅, 江红, 邹振   

  1. 中国科学院动物研究所, 农业虫害鼠害综合治理研究国家重点实验室, 北京 100101
  • 通讯作者: 邹振,
  • 作者简介:王燕红(1982-),女,博士后,主要从事蚊虫免疫和昆虫毒理学研究。
  • 基金资助:



As an important vector for insect-borne diseases, mosquitoes transmit viral encephalitis, dengue, malaria, filariasis and others and cause great concern to human health. The prevention and control of mosquito vectors is an important measure for controlling these infectious diseases. Mosquitoes have developed innate immunity against pathogens such as viruses, fungi and parasites. The immunity of mosquitoes is mainly classified into humoral immunity and cellular immunity. Complement recognition and activation system, immune signaling pathways, melanization, reactive oxygen species, etc. are involved in the immune response to pathogens. This paper reviews the recent research progress in the immune response mechanism against pathogens such as malaria parasites and fungi in mosquito vectors, which will provide theoretical support for developing new mosquito control strategies.

Key words: Mosquito, Humoral immunity, Cellular immunity, Plasmodium, Entomogenous fungus



关键词: 蚊虫, 体液免疫, 细胞免疫, 疟原虫, 虫生真菌

CLC Number: