Wolbachia, a maternally transmitted obligate endosymbiotic gramnegative bacteria, is widely distributed in invertebrates. The Wolbachia?mediated biological control of mosquito and mosquito?borne diseases is based on the nature that Wolbachia induces cytoplasmic incompatibility, and reduces the vector competence of its host species. Wolbachia induced pathogen inhibition in mosquito is broad?spectrum, its size is larger than mosquito’s salivary gland duct so it is impossible to be transmitted to humans or mammals through mosquito bitin. Antibodies against Wolbachia have never been detected in blood of humans who are repeatedly bitten by mosquitoes which are infected with Wolbachia. Wolbachia cannot produce spores and does not contain plasmid, it will not disseminate to the environment when its host dies. Wolbachia cannot be horizontally transmitted from one invertebrate host to another that lives in the same environment. Invertebrate predators that feed on Wolbachia?infected mosquito larvae or adults do not get infected. The biological risks of Wolbachia?mediated biological control of mosquito and mosquito?borne diseases are negligible.
ZHENG Xiaoying, LIU Qiyong, , XI Zhiyong,
. The biosafety concerns of Wolbachia?mediated biological controlof mosquitoes and mosquito-borne diseases[J]. Chinese Journal of Vector Biology and Control, 2014
, 25(2)
: 93
-96
.
DOI: 10.11853/j.issn.1003.4692.2014.02.001
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