Chines Journal of Vector Biology and Control ›› 2019, Vol. 30 ›› Issue (6): 725-728.DOI: 10.11853/j.issn.1003.8280.2019.06.032

• Review • Previous Articles    

Advances in research on anticoagulant rodenticide resistance

DU Guo-yi, YAN Dong, WANG Zhi-yu, GAO Shao-kun   

  1. Anti-plague Institute of Hebei Province, Zhangjiakou 075000, Hebei Province, China
  • Received:2019-08-22 Online:2019-12-20 Published:2019-12-20
  • Supported by:
    Supported by the Key Medical Projects of Hebei Province (No. 20180955) and the Key Subjects of Medical Science Research in Hebei Province in 2010 (No. 20100225)

抗凝血杀鼠剂抗药性的研究进展

杜国义, 闫东, 王治宇, 高少坤   

  1. 河北省鼠疫防治所, 河北 张家口 075000
  • 作者简介:杜国义,男,主任医师,从事鼠疫防治工作,Email:530258017@qq.com
  • 基金资助:
    2018年河北省医学重点项目(20180955);河北省2010年医学科学研究重点课题计划项目(20100225)

Abstract: In recent years, a lot of research on anticoagulant rodenticide resistance, conducted by scholars at home and abroad, show that continuous use of anticoagulant rodenticides for 6 to 10 years will lead to rodenticide resistance in rodents. Rodenticide resistance can be effectively controlled by active resistance monitoring, scientific and rational use of drugs, cautious replacement of anticoagulant rodenticides, and integrated management and scientific rodent control. This paper summarizes the commonly used research methods and detection standards for anticoagulant rodenticide resistance at present, analyzes the cause of resistance, and discusses the current problems and shortcomings in the research on anticoagulant rodenticide resistance. Then management strategies and measures for anticoagulant rodenticide resistance are proposed to provide a reference for scientific rodent control.

Key words: Anticoagulant rodenticides, Rodenticide resistance

摘要: 近些年,国内外许多学者针对抗凝血杀鼠剂的抗药性做了大量研究,结果表明,抗凝血杀鼠剂连续使用6~10年鼠类会对其产生抗药性。积极开展抗药性监测,科学合理使用药物,谨慎更换抗凝血杀鼠剂,开展综合治理、科学灭鼠等措施可以有效防止抗药性的发生。该文概述了目前常用的抗凝血杀鼠剂抗药性研究方法和抗药性检测标准,分析了产生抗药性的原因,探讨现阶段抗凝血杀鼠剂抗药性研究领域存在的问题和不足,提出对抗凝血杀鼠剂抗药性的策略和措施,为科学灭鼠工作提供参考。

关键词: 抗凝血杀鼠剂, 抗药性

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